Born in Ghent, De Vreese has competed as a professional since the start of the 2011 season, riding as a member of the Topsport Vlaanderen–Mercator squad. At the 2012 running of Liège–Bastogne–Liège, De Vreese was one of a number of riders to be disqualified from the event as a result of taking a short-cut.^[3]

De Vreese left Topsport Vlaanderen–Baloise at the end of the 2013 season and joined Wanty–Groupe Gobert for the 2014 season.^[4]Subsequently in August 2014 Team Astana announced that De Vreese had signed a one year deal with the squad for 2015.^[5]